If you’ve ever said, “I want Botox,” you might be surprised to learn that Botox is just one of several wrinkle-relaxing injectables on the market today. In 2023, the FDA approved Letybo, a new neuromodulator from South Korea that’s now available at Spa Bella Medispa — giving our Denver clients yet another option to smooth expression lines and soften signs of aging.
So how do you choose between Botox, Letybo, Dysport, and Xeomin? While they all fall under the same category — injectable botulinum toxin type A — there are subtle differences in how they perform, how fast they work, and what kind of results you can expect.
Here’s what you need to know.
What Do These Injectables Actually Do?
All four products temporarily relax the muscles that cause dynamic wrinkles — the fine lines that form from repetitive movement like smiling, frowning, or squinting. Common treatment areas include:
- Forehead lines
- Frown lines (a.k.a. “11s”)
- Crow’s feet
- Lip lines, bunny lines, jawline slimming, and more
Each brand uses a slightly different formulation, which affects how quickly it kicks in, how long it lasts, and how it spreads in the muscle.
Botox vs. Letybo vs. Dysport vs. Xeomin: At-a-Glance Comparison
| Feature | Botox | Dysport | Xeomin | Letybo |
|---|---|---|---|---|
| FDA Approval | 2002 | 2009 | 2010 | 2023 |
| Origin | Allergan (USA) | Ipsen (France) | Merz (Germany) | Hugel (South Korea) |
| Molecule Type | Complexed | Complexed | Naked (no additives) | Complexed |
| Speed of Onset | 3–5 days | 2–3 days (fastest) | 3–4 days | 3–5 days (early data) |
| Duration | 3–4 months | 3–4 months | 3–4 months | 3–4 months (based on clinical data) |
| Unique Edge | Most studied, gold standard | Spreads well, quick results | Minimalist, pure toxin | Smooth spread, often more affordable |
| Pro Tip | Great for tried-and-true users | Good for wide forehead coverage and fast results | Best for sensitive skin | Promising option for new patients & natural look |
How to Choose the Right Neuromodulator
Everyone’s face — and goals — are different. Here’s how we help our clients at Spa Bella decide:
Choose Botox if…
You want a proven, predictable result and have been happy with Botox in the past. Great for first-timers or those wanting a conservative, classic result.
Choose Dysport if…
You want fast results (in 2–3 days), especially for larger treatment areas like the forehead. It may diffuse more, which can be great for broad muscle zones.
Choose Xeomin if…
You have sensitive skin, allergies, or simply prefer a product without unnecessary proteins or preservatives. Known as the “naked injectable,” Xeomin may reduce the risk of antibody resistance over time.
Choose Letybo if…
You’re curious about the latest innovation in aesthetics, or want a wrinkle relaxer that provides a smooth, natural look with competitive pricing. Early clinical data shows high patient satisfaction and similar duration to Botox.
Can I Switch Between These?
Yes. Many clients rotate or switch brands based on their aesthetic goals, budget, or even how they respond to the product over time. At Spa Bella, we’ll review your history, assess your facial anatomy, and help you choose the best fit at each visit.
Why Choose Spa Bella Medispa for Neuromodulators?
Our expert injectors in Denver are known for natural, customized results — never frozen, never overdone. We stay up to date with the newest products, like Letybo, while maintaining the skill and knowledge to work with all FDA-approved options.
Every face is different — and we believe every treatment plan should be too. Book a consultation today and let us guide you toward the perfect choice for your skin, movement patterns, and aesthetic goals.